Merck Manual Home Health Handbook states that the color characteristic bright red blood is a byproduct of protein hemoglobin, which is found in all red blood cells. Hemoglobin binds oxygen molecules individually, allowing red blood cells to carry them to the entire cardiovascular system.
University of Rochester Medical Center explains the red blood cells have a spherical shape, slightly flat, disk-like cells with indented center. Red blood cells produced in the bone marrow, which is found in some types of bone. Individual red blood cells live for about 120 days.
Merck Manual Home Health Handbook reports that the red blood cells are the most prolific solid component found in the blood and store about 40 percent of the volume. Other solids found in the blood are white blood cells and platelets. Blood solid components suspended in a liquid called plasma, with more than half of the total blood volume.
Erythrocyte
Erythrocytes, also known as red blood cells, serves to carry oxygen in the blood. Erythrocyte shape is ideal for this function. Seen from above, erythrocytes appear circular, but in terms of showing that they actually biconcave discs. This shape increases the surface area to volume ratio of the cell, thereby increasing the efficiency of the diffusion of oxygen and carbon dioxide into and out of cells. Erythrocytes also has a flexible plasma membrane. This feature allows the erythrocytes, which has a diameter of 7 micrometers, to squeeze through capillaries as small as the width of 3 micrometers. Erythrocytes contain large amounts of hemoglobin, the protein that binds oxygen.In order to create more space for hemoglobin carries more oxygen, erythrocytes lose their nucleus and other organelles as they develop in the bone marrow. Because they lack a nucleus and other cellular machinery, erythrocytes can not repair itself when damaged, as a result they have a limited life span of about 120 days. Elimination of old and dying erythrocytes conducted by the spleen. Erythrocytes, which is a type of cell in the body most die at high speed, 2-3 million erythrocytes die every second. Erythrocyte production must be equal to the death of erythrocytes or cell populations will decrease. Erythrocytes are produced through a process called erythropoiesis.
Erythrocytes, or red blood cells, forming the largest population of blood cells, which numbered 4500000-6000000 per cubic millimeter of blood. They perform the exchange of oxygen and carbon dioxide between the lungs and body tissues. To effectively combine with oxygen, erythrocytes should contain the normal number of red pigment hemoglobin protein, the amount of which in turn depends on the level of iron in the body. Lack of iron and hemoglobin can lead to anemia and poor oxygenation of tissues.
Erythrocytes continues to grow from stem cells, differentiated cells to regenerate themselves that give rise to erythrocytes and leukocytes in the bone marrow.
In the fetus, the red blood cells produced in the spleen. As they mature, the erythrocytes lose their core, the form of discs, and began to produce hemoglobin. After circulating for about 120 days, erythrocytes undergo wear and destruction by the spleen. Despite all the red blood cells are basically the same, specific structures on their surface varies in each person. It serves as a basis for classification into the blood groups. There are four major blood groups, the compatibility or incompatibility is an important consideration in a successful blood transfusions.
Red blood cells are highly specialized, able to adapt to their primary function of which is to carry oxygen from the lungs to all body tissues. Red blood cells have a diameter of about 7.8 micrometers and has a double concave disc shape, the shape that gives the ratio of surface-to-volume. When the fresh blood under a microscope, the red blood cells appear yellow-green disc with a pale center does not contain an internal structure that is visible. When blood is centrifuged cause the cells can be separated, the volume of red blood cells packed tightly (hematocrit value) ranged between 42 and 54 percent of the total volume in men and between 37 and 47 percent in women; these values are slightly lower in children. Normal red blood cells are fairly uniform in volume, so that the hematocrit value is determined primarily by the number of red blood cells per unit of blood. Count of red blood cells which normally ranges between four million and six million per cubic millimeter. Thank you for reading this article.
Written and posted by Bambang Sunarno. sunarnobambang86@gmail.com
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DatePublished: 11 September 2015 11:00
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